Intracerebral Transplantation of Adult Mouse Neural Progenitor Cells into the Niemann-Pick-A Mouse Leads to a Marked Decrease in Lysosomal Storage Pathology

Niemann-Pick disease is caused by a genetic deficiency in acid sphingomyelinase (ASM) leading to the intracellular accumulation of sphingomyelin and cholesterol in lysosomes. In the present study, we evaluated the effects of direct intracerebral transplantation of neural progenitor cells (NPCs) on t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Shihabuddin, L. S., Numan, S., Huff, M. R., Dodge, J. C., Clarke, J., Macauley, S. L., Yang, W., Taksir, T. V., Parsons, G., Passini, M. A., Gage, F. H., Stewart, G. R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2004
Pynciau:
Neurobiology of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730128/
https://ncbi.nlm.nih.gov/pubmed/15564580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3584-04.2004
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