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Locking the Dimeric GABA(B) G-Protein-Coupled Receptor in Its Active State

G-protein-coupled receptors (GPCRs) play a major role in cell-cell communication in the CNS. These proteins oscillate between various inactive and active conformations, the latter being stabilized by agonists. Although mutations can lead to constitutive activity, most of these destabilize inactive c...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Kniazeff, Julie, Saintot, Pierre-Philippe, Goudet, Cyril, Liu, Jianfeng, Charnet, Annie, Guillon, Gilles, Pin, Jean-Philippe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729975/
https://ncbi.nlm.nih.gov/pubmed/14724235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3141-03.2004
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