Locking the Dimeric GABA(B) G-Protein-Coupled Receptor in Its Active State

G-protein-coupled receptors (GPCRs) play a major role in cell-cell communication in the CNS. These proteins oscillate between various inactive and active conformations, the latter being stabilized by agonists. Although mutations can lead to constitutive activity, most of these destabilize inactive c...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Kniazeff, Julie, Saintot, Pierre-Philippe, Goudet, Cyril, Liu, Jianfeng, Charnet, Annie, Guillon, Gilles, Pin, Jean-Philippe
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2004
Gaiak:
Cellular/Molecular
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729975/
https://ncbi.nlm.nih.gov/pubmed/14724235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3141-03.2004
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