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Highly Selective and Prolonged Depletion of Mitochondrial Glutathione in Astrocytes Markedly Increases Sensitivity to Peroxynitrite

Glutathione, a major endogenous antioxidant, is found in two intracellular pools in the cytoplasm and the mitochondria. To investigate the importance of the smaller mitochondrial pool, we developed conditions based on treatment with ethacrynic acid that produced near-complete and highly selective de...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Muyderman, Håkan, Nilsson, Michael, Sims, Neil R.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729783/
https://ncbi.nlm.nih.gov/pubmed/15371502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1103-04.2004
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