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Neuroprotection against neuroblastoma cell death induced by depletion of mitochondrial glutathione

Mitochondrial glutathione pool is vital in protecting cells against oxidative stress as the majority of the cellular reactive oxygen species are generated in mitochondria. Oxidative stress is implicated as a causative factor in neuronal death in neurodegenerative disorders. We hypothesized that depl...

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Autors principals: Dukhande, Vikas V., Kawikova, Ivana, Bothwell, Alfred L.M., Lai, James C.K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645366/
https://ncbi.nlm.nih.gov/pubmed/23494481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-013-0836-4
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