Neuroprotective effects of donepezil against cholinergic depletion

INTRODUCTION: Intraparenchymal injections of the immunotoxin 192-IgG-saporin into medial septum and nucleus basalis magnocellularis causes a selective depletion of basal forebrain cholinergic neurons. Thus, it represents a valid model to mimic a key component of the cognitive deficits associated wit...

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Main Authors: Cutuli, Debora, De Bartolo, Paola, Caporali, Paola, Tartaglione, Anna Maria, Oddi, Diego, D’Amato, Francesca Romana, Nobili, Annalisa, D’Amelio, Marcello, Petrosini, Laura
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978431/
https://ncbi.nlm.nih.gov/pubmed/24401551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt215
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