Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione—L-Dopa Codrug Against H(2)O(2)-Induced Cellular Toxicity

The L-3,4-dihydroxyphenylalanine (LD) is the gold standard drug currently used to manage Parkinson’s disease (PD) and to control its symptoms. However, LD could cause disease neurotoxicity due to the generation of pro-oxidant intermediates deriving from its autoxidation. In order to overcome this li...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antioxidants (Basel)
Main Authors: Franceschelli, Sara, Lanuti, Paola, Ferrone, Alessio, Gatta, Daniela Maria Pia, Speranza, Lorenza, Pesce, Mirko, Grilli, Alfredo, Cacciatore, Ivana, Ricciotti, Emanuela, Di Stefano, Antonio, Miscia, Sebastiano, Felaco, Mario, Patruno, Antonia
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI 2019
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720001/
https://ncbi.nlm.nih.gov/pubmed/31430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8080319
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