Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione—L-Dopa Codrug Against H(2)O(2)-Induced Cellular Toxicity

The L-3,4-dihydroxyphenylalanine (LD) is the gold standard drug currently used to manage Parkinson’s disease (PD) and to control its symptoms. However, LD could cause disease neurotoxicity due to the generation of pro-oxidant intermediates deriving from its autoxidation. In order to overcome this li...

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Bibliografiset tiedot
Julkaisussa:Antioxidants (Basel)
Päätekijät: Franceschelli, Sara, Lanuti, Paola, Ferrone, Alessio, Gatta, Daniela Maria Pia, Speranza, Lorenza, Pesce, Mirko, Grilli, Alfredo, Cacciatore, Ivana, Ricciotti, Emanuela, Di Stefano, Antonio, Miscia, Sebastiano, Felaco, Mario, Patruno, Antonia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720001/
https://ncbi.nlm.nih.gov/pubmed/31430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8080319
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