Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione—L-Dopa Codrug Against H(2)O(2)-Induced Cellular Toxicity

The L-3,4-dihydroxyphenylalanine (LD) is the gold standard drug currently used to manage Parkinson’s disease (PD) and to control its symptoms. However, LD could cause disease neurotoxicity due to the generation of pro-oxidant intermediates deriving from its autoxidation. In order to overcome this li...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Franceschelli, Sara, Lanuti, Paola, Ferrone, Alessio, Gatta, Daniela Maria Pia, Speranza, Lorenza, Pesce, Mirko, Grilli, Alfredo, Cacciatore, Ivana, Ricciotti, Emanuela, Di Stefano, Antonio, Miscia, Sebastiano, Felaco, Mario, Patruno, Antonia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720001/
https://ncbi.nlm.nih.gov/pubmed/31430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8080319
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