Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione—L-Dopa Codrug Against H(2)O(2)-Induced Cellular Toxicity

The L-3,4-dihydroxyphenylalanine (LD) is the gold standard drug currently used to manage Parkinson’s disease (PD) and to control its symptoms. However, LD could cause disease neurotoxicity due to the generation of pro-oxidant intermediates deriving from its autoxidation. In order to overcome this li...

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Bibliografiske detaljer
Udgivet i:Antioxidants (Basel)
Main Authors: Franceschelli, Sara, Lanuti, Paola, Ferrone, Alessio, Gatta, Daniela Maria Pia, Speranza, Lorenza, Pesce, Mirko, Grilli, Alfredo, Cacciatore, Ivana, Ricciotti, Emanuela, Di Stefano, Antonio, Miscia, Sebastiano, Felaco, Mario, Patruno, Antonia
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720001/
https://ncbi.nlm.nih.gov/pubmed/31430883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8080319
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