Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion

ATP-binding cassette (ABC) transpo rters ABCC1 (MRP1), ABCB1 (P-gp), and ABCG2 (BCRP) contribute to chemotherapy failure. The primary goals of this study were to characterize the efficacy and mechanism of the non­steroidal anti-inflammatory drug (NSAID), sulindac sulfide, to reverse ABCC1 mediated r...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biomed Res
Main Authors: Whitt, Jason D., Keeton, Adam B., Gary, Bernard D., Sklar, Larry A., Sodani, Kamlesh, Chen, Zhe-Sheng, Piazza, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4820889/
https://ncbi.nlm.nih.gov/pubmed/28276667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.30.20150108
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados