Huntingtin Bodies Sequester Vesicle-Associated Proteins by a Polyproline-Dependent Interaction

Polyglutamine expansion in the N terminus of huntingtin (htt) causes selective neuronal dysfunction and cell death by unknown mechanisms. Truncated htt expressed in vitro produced htt immunoreactive cytoplasmic bodies (htt bodies). The fibrillar core of the mutant htt body resisted protease treatmen...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Qin, Zheng-Hong, Wang, Yumei, Sapp, Ellen, Cuiffo, Benjamin, Wanker, Erich, Hayden, Michael R., Kegel, Kimberly B., Aronin, Neil, DiFiglia, Marian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2004
Onderwerpen:
Neurobiology of Disease
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729557/
https://ncbi.nlm.nih.gov/pubmed/14715959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1409-03.2004
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items