Choline Transporter 1 Maintains Cholinergic Function in Choline Acetyltransferase Haploinsufficiency

Choline acetyltransferase (ChAT), the enzyme that synthesizes the neurotransmitter acetylcholine (ACh), is thought to be present in kinetic excess in cholinergic neurons. The rate-limiting factor in ACh production is the provision of choline to ChAT. Cholinergic neurons are relatively unique in thei...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Brandon, Eugene P., Mellott, Tiffany, Pizzo, Donald P., Coufal, Nicole, D'Amour, Kevin A., Gobeske, Kevin, Lortie, Mark, López-Coviella, Ignacio, Berse, Brygida, Thal, Leon J., Gage, Fred H., Blusztajn, Jan Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Behavioral/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729318/
https://ncbi.nlm.nih.gov/pubmed/15201317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1106-04.2004
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