Choline Transporter 1 Maintains Cholinergic Function in Choline Acetyltransferase Haploinsufficiency

Choline acetyltransferase (ChAT), the enzyme that synthesizes the neurotransmitter acetylcholine (ACh), is thought to be present in kinetic excess in cholinergic neurons. The rate-limiting factor in ACh production is the provision of choline to ChAT. Cholinergic neurons are relatively unique in thei...

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Pubblicato in:J Neurosci
Autori principali: Brandon, Eugene P., Mellott, Tiffany, Pizzo, Donald P., Coufal, Nicole, D'Amour, Kevin A., Gobeske, Kevin, Lortie, Mark, López-Coviella, Ignacio, Berse, Brygida, Thal, Leon J., Gage, Fred H., Blusztajn, Jan Krzysztof
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
Soggetti:
Behavioral/Systems/Cognitive
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729318/
https://ncbi.nlm.nih.gov/pubmed/15201317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1106-04.2004
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