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Cholinergic activity is essential for maintaining the anterograde transport of Choline Acetyltransferase in Drosophila

Cholinergic activity is essential for cognitive functions and neuronal homeostasis. Choline Acetyltransferase (ChAT), a soluble protein that synthesizes acetylcholine at the presynaptic compartment, is transported in bulk in the axons by the heterotrimeric Kinesin-2 motor. Axonal transport of solubl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dey, Swagata, Ray, Krishanu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966444/
https://ncbi.nlm.nih.gov/pubmed/29795337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26176-z
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