Choline Transporter 1 Maintains Cholinergic Function in Choline Acetyltransferase Haploinsufficiency

Choline acetyltransferase (ChAT), the enzyme that synthesizes the neurotransmitter acetylcholine (ACh), is thought to be present in kinetic excess in cholinergic neurons. The rate-limiting factor in ACh production is the provision of choline to ChAT. Cholinergic neurons are relatively unique in thei...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Brandon, Eugene P., Mellott, Tiffany, Pizzo, Donald P., Coufal, Nicole, D'Amour, Kevin A., Gobeske, Kevin, Lortie, Mark, López-Coviella, Ignacio, Berse, Brygida, Thal, Leon J., Gage, Fred H., Blusztajn, Jan Krzysztof
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2004
Fag:
Behavioral/Systems/Cognitive
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729318/
https://ncbi.nlm.nih.gov/pubmed/15201317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1106-04.2004
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