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Choline Transporter 1 Maintains Cholinergic Function in Choline Acetyltransferase Haploinsufficiency

Choline acetyltransferase (ChAT), the enzyme that synthesizes the neurotransmitter acetylcholine (ACh), is thought to be present in kinetic excess in cholinergic neurons. The rate-limiting factor in ACh production is the provision of choline to ChAT. Cholinergic neurons are relatively unique in thei...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Brandon, Eugene P., Mellott, Tiffany, Pizzo, Donald P., Coufal, Nicole, D'Amour, Kevin A., Gobeske, Kevin, Lortie, Mark, López-Coviella, Ignacio, Berse, Brygida, Thal, Leon J., Gage, Fred H., Blusztajn, Jan Krzysztof
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729318/
https://ncbi.nlm.nih.gov/pubmed/15201317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1106-04.2004
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