Choline Transporter 1 Maintains Cholinergic Function in Choline Acetyltransferase Haploinsufficiency

Choline acetyltransferase (ChAT), the enzyme that synthesizes the neurotransmitter acetylcholine (ACh), is thought to be present in kinetic excess in cholinergic neurons. The rate-limiting factor in ACh production is the provision of choline to ChAT. Cholinergic neurons are relatively unique in thei...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Brandon, Eugene P., Mellott, Tiffany, Pizzo, Donald P., Coufal, Nicole, D'Amour, Kevin A., Gobeske, Kevin, Lortie, Mark, López-Coviella, Ignacio, Berse, Brygida, Thal, Leon J., Gage, Fred H., Blusztajn, Jan Krzysztof
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2004
Sujets:
Behavioral/Systems/Cognitive
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729318/
https://ncbi.nlm.nih.gov/pubmed/15201317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1106-04.2004
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