Rescue of Mesencephalic Dopaminergic Neurons in Culture by Low-Level Stimulation of Voltage-Gated Sodium Channels

We used a model system in which dopaminergic (DA) neurons from embryonic rat mesencephalon undergo spontaneous and selective degeneration as they develop in culture. Here, we show that DA cell loss can be prevented efficiently by low concentrations of the Na(+) channel agonist veratridine. The survi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Salthun-Lassalle, Bénédicte, Hirsch, Etienne C., Wolfart, Jakob, Ruberg, Merle, Michel, Patrick P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2004
Gaiak:
Development/Plasticity/Repair
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729237/
https://ncbi.nlm.nih.gov/pubmed/15229240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5668-03.2004
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