Rescue of Mesencephalic Dopaminergic Neurons in Culture by Low-Level Stimulation of Voltage-Gated Sodium Channels

We used a model system in which dopaminergic (DA) neurons from embryonic rat mesencephalon undergo spontaneous and selective degeneration as they develop in culture. Here, we show that DA cell loss can be prevented efficiently by low concentrations of the Na(+) channel agonist veratridine. The survi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Salthun-Lassalle, Bénédicte, Hirsch, Etienne C., Wolfart, Jakob, Ruberg, Merle, Michel, Patrick P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729237/
https://ncbi.nlm.nih.gov/pubmed/15229240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5668-03.2004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados