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Excitability Constraints on Voltage-Gated Sodium Channels

We study how functional constraints bound and shape evolution through an analysis of mammalian voltage-gated sodium channels. The primary function of sodium channels is to allow the propagation of action potentials. Since Hodgkin and Huxley, mathematical models have suggested that sodium channel pro...

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書誌詳細
主要な著者: Angelino, Elaine, Brenner, Michael P
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1988852/
https://ncbi.nlm.nih.gov/pubmed/17892320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030177
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