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Excitability Constraints on Voltage-Gated Sodium Channels
We study how functional constraints bound and shape evolution through an analysis of mammalian voltage-gated sodium channels. The primary function of sodium channels is to allow the propagation of action potentials. Since Hodgkin and Huxley, mathematical models have suggested that sodium channel pro...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1988852/ https://ncbi.nlm.nih.gov/pubmed/17892320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030177 |
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