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Flufenamic acid decreases neuronal excitability through modulation of voltage-gated sodium channel gating
The electrophysiological phenotype of individual neurons critically depends on the biophysical properties of the voltage-gated channels they express. Differences in sodium channel gating are instrumental in determining the different firing phenotypes of pyramidal cells and interneurons; moreover, so...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000579/ https://ncbi.nlm.nih.gov/pubmed/20724367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.193037 |
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