Flufenamic acid decreases neuronal excitability through modulation of voltage-gated sodium channel gating

The electrophysiological phenotype of individual neurons critically depends on the biophysical properties of the voltage-gated channels they express. Differences in sodium channel gating are instrumental in determining the different firing phenotypes of pyramidal cells and interneurons; moreover, so...

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Bibliographic Details
Main Authors: Yau, Hau-Jie, Baranauskas, Gytis, Martina, Marco
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2010
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000579/
https://ncbi.nlm.nih.gov/pubmed/20724367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.193037
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