Inhibition of CHK 1 (Checkpoint Kinase 1) Elicits Therapeutic Effects in Pulmonary Arterial Hypertension

OBJECTIVE: Pulmonary arterial hypertension (PAH) is a debilitating disease associated with progressive vascular remodeling of distal pulmonary arteries leading to elevation of pulmonary artery pressure, right ventricular hypertrophy, and death. Although presenting high levels of DNA damage that norm...

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Bibliografiska uppgifter
I publikationen:Arterioscler Thromb Vasc Biol
Huvudupphovsmän: Bourgeois, Alice, Bonnet, Sébastien, Breuils-Bonnet, Sandra, Habbout, Karima, Paradis, Renée, Tremblay, Eve, Lampron, Marie-Claude, Orcholski, Mark E., Potus, Francois, Bertero, Thomas, Peterlini, Thibaut, Chan, Stephen Y., Norris., Karen A, Paulin, Roxane, Provencher, Steeve, Boucherat, Olivier
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6727643/
https://ncbi.nlm.nih.gov/pubmed/31092016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.119.312537
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