HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with limited therapeutic options. Although exposed to stressful conditions, pulmonary artery (PA) smooth muscle cells (PASMCs) exhibit a “cancer-like” pro-proliferative and anti-apoptotic phenotype. HDAC6 is a cytoplasmic histone...

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Pubblicato in:Sci Rep
Autori principali: Boucherat, Olivier, Chabot, Sophie, Paulin, Roxane, Trinh, Isabelle, Bourgeois, Alice, Potus, François, Lampron, Marie-Claude, Lambert, Caroline, Breuils-Bonnet, Sandra, Nadeau, Valérie, Paradis, Renée, Goncharova, Elena A., Provencher, Steeve, Bonnet, Sébastien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495763/
https://ncbi.nlm.nih.gov/pubmed/28674407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04874-4
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