Dual ET(A)/ET(B) blockade with macitentan improves both vascular remodeling and angiogenesis in pulmonary arterial hypertension

Dysregulated metabolism and rarefaction of the capillary network play a critical role in pulmonary arterial hypertension (PAH) etiology. They are associated with a decrease in perfusion of the lungs, skeletal muscles, and right ventricle (RV). Previous studies suggested that endothelin-1 (ET-1) modu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pulm Circ
Main Authors: Nadeau, Valerie, Potus, Francois, Boucherat, Olivier, Paradis, Renee, Tremblay, Eve, Iglarz, Marc, Paulin, Roxane, Bonnet, Sebastien, Provencher, Steeve
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731731/
https://ncbi.nlm.nih.gov/pubmed/29064353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045893217741429
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados