APE1 upregulates MMP-14 via redox-sensitive ARF6-mediated recycling to promote cell invasion of esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) is an aggressive malignancy with poor clinical outcome. The incidence of EAC has been rising rapidly in the past three decades. Here, we showed that apurinic/apyrimidinic endonuclease (APE1) is overexpressed in EAC cell lines, and patients' samples of dysplasia a...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Lu, Heng, Bhat, Ajaz A., Peng, Dunfa, Chen, Zheng, Zhu, Shoumin, Hong, Jun, Maacha, Selma, Yan, Jin, Robbins, David J., Washington, M. Kay, Belkhiri, Abbes, El-Rifai, Wael
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726537/
https://ncbi.nlm.nih.gov/pubmed/31308045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-0237
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