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Transcriptional upregulation of c‐MYC by AXL confers epirubicin resistance in esophageal adenocarcinoma

AXL receptor tyrosine kinase is overexpressed in esophageal adenocarcinoma (EAC) and several other types of malignancies; hence, it may be a valuable therapeutic target. Herein, we investigated the role of AXL in regulating c‐MYC expression and resistance to the chemotherapeutic agent epirubicin in...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Hong, Jun, Maacha, Selma, Belkhiri, Abbes
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6275285/
https://ncbi.nlm.nih.gov/pubmed/30353671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12395
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