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Toll-Like Receptor 4 on Nonhematopoietic Cells Sustains CNS Inflammation during Endotoxemia, Independent of Systemic Cytokines

Inflammatory agonists such as lipopolysaccharide (LPS) induce robust systemic as well as CNS responses after peripheral administration. Responses in the innate immune system require triggering of toll-like receptor 4 (TLR4), but the origin of CNS sequelas has been controversial. We demonstrate expre...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chakravarty, Sumana, Herkenham, Miles
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725921/
https://ncbi.nlm.nih.gov/pubmed/15716415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4268-04.2005
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