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Discovery of Imidazoquinolines with Toll-Like Receptor 7/8 Independent Cytokine Induction
[Image: see text] Toll-like receptors (TLRs) are key targets in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments. The imidazoquinolines, imiquimod and resiquimod, have been shown to activate TLR-7 and -8, which in turn induce cytokine production as part of...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402226/ https://ncbi.nlm.nih.gov/pubmed/22837811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300079e |
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