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Bacterial lipopolysaccharide fever is initiated via Toll-like receptor 4 on hematopoietic cells

Lipopolysaccharide (LPS), a well-known bacterial pyrogen, is recognized by several receptors, including the Toll-like receptor 4 (TLR4), on various cells. Which of these receptors and cells are linked to fever production is unknown. By constructing 4 mouse chimeras and studying their thermoregulator...

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Autors principals: Steiner, Alexandre A., Chakravarty, Sumana, Rudaya, Alla Y., Herkenham, Miles, Romanovsky, Andrej A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Hematology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895291/
https://ncbi.nlm.nih.gov/pubmed/16403908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-4743
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