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Human Toll-like Receptor 2 Confers Responsiveness to Bacterial Lipopolysaccharide
Bacterial lipopolysaccharide (LPS) induces activation of the transcription factor nuclear factor κB (NF-κB) in host cells upon infection. LPS binds to the glycosylphosphatidylinositol (GPI)- anchored membrane protein CD14, which lacks an intracellular signaling domain. Here we investigated the role...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212382/ https://ncbi.nlm.nih.gov/pubmed/9841923 |
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