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MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4

Toll-like receptor 4 (TLR4) is a mammalian homologue of Drosophila Toll, a leucine-rich repeat molecule that can trigger innate responses against pathogens. The TLR4 gene has recently been shown to be mutated in C3H/HeJ and C57BL/10ScCr mice, both of which are low responders to lipopolysaccharide (L...

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Détails bibliographiques
Auteurs principaux: Shimazu, Rintaro, Akashi, Sachiko, Ogata, Hirotaka, Nagai, Yoshinori, Fukudome, Kenji, Miyake, Kensuke, Kimoto, Masao
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193086/
https://ncbi.nlm.nih.gov/pubmed/10359581
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