Induction of Long-Term Lipopolysaccharide Tolerance by an Agonistic Monoclonal Antibody to the Toll-Like Receptor 4/MD-2 Complex

We have established an agonistic monoclonal antibody, UT12, that induces stimulatory signals comparable to those induced by lipopolysaccharide (LPS) through Toll-like receptor 4 and MD-2. UT12 activated nuclear factor κB and induced the production of proinflammatory cytokines such as tumor necrosis...

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Detalhes bibliográficos
Main Authors: Ohta, Shoichiro, Bahrun, Uleng, Shimazu, Rintaro, Matsushita, Hidetomo, Fukudome, Kenji, Kimoto, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Cellular Immunology, Antibodies, and Mediators of Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1595322/
https://ncbi.nlm.nih.gov/pubmed/17028215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00173-06
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