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Platelet-activating factor is a potent pyrogen and cryogen, but it does not mediate lipopolysaccharide fever or hypothermia

We examined whether platelet-activating factor (PAF) and its receptor mediate lipopolysaccharide (LPS)-induced fever and hypothermia in rats. Two highly potent, structurally distinct antagonists of the PAF receptor, CV6209 and WEB2086, were used. At a neutral ambient temperature (T(a)) of 30ºC, admi...

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Detaylı Bibliyografya
Yayımlandı:Temperature (Austin)
Asıl Yazarlar: Steiner, Alexandre A, Romanovsky, Andrej A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843927/
https://ncbi.nlm.nih.gov/pubmed/27227073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23328940.2015.1030540
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