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Cyclooxygenase-1 or -2—which one mediates lipopolysaccharide-induced hypothermia?
Systemic inflammation is associated with either fever or hypothermia. Fever, a response to mild systemic inflammation, is mediated by cyclooxygenase (COX)-2 and not by COX-1. However, it is still disputed whether COX-2, COX-1, neither, or both mediate(s) responses to severe systemic inflammation, an...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2724239/ https://ncbi.nlm.nih.gov/pubmed/19515980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.91026.2008 |
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