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Mechanism of Positive Allosteric Modulators Acting on AMPA Receptors

Ligand-gated ion channels involved in the modulation of synaptic strength are the AMPA, kainate, and NMDA glutamate receptors. Small molecules that potentiate AMPA receptor currents relieve cognitive deficits caused by neurodegenerative diseases such as Alzheimer's disease and show promise in t...

詳細記述

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書誌詳細
出版年:J Neurosci
主要な著者: Jin, Rongsheng, Clark, Suzanne, Weeks, Autumn M., Dudman, Joshua T., Gouaux, Eric, Partin, Kathryn M.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725607/
https://ncbi.nlm.nih.gov/pubmed/16192394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2567-05.2005
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