Mechanism of Positive Allosteric Modulators Acting on AMPA Receptors

Ligand-gated ion channels involved in the modulation of synaptic strength are the AMPA, kainate, and NMDA glutamate receptors. Small molecules that potentiate AMPA receptor currents relieve cognitive deficits caused by neurodegenerative diseases such as Alzheimer's disease and show promise in t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Jin, Rongsheng, Clark, Suzanne, Weeks, Autumn M., Dudman, Joshua T., Gouaux, Eric, Partin, Kathryn M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2005
Gaiak:
Cellular/Molecular
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725607/
https://ncbi.nlm.nih.gov/pubmed/16192394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2567-05.2005
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