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Downregulation of Cytosolic Prostaglandin E(2) Synthase Results in Decreased Nociceptive Behavior in Rats
Nociception-evoked prostaglandin E(2) (PGE(2)) release in the spinal cord contributes considerably to the development of hyperalgesia and allodynia. Biosynthesis of PGE(2) involves the conversion of arachidonic acid to PGH(2) by cyclooxygenases (COXs), followed by an isomerization of PGH(2) to PGE(2...
Kaydedildi:
| Yayımlandı: | J Neurosci |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Neuroscience
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725604/ https://ncbi.nlm.nih.gov/pubmed/16192391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2190-05.2005 |
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