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Downregulation of Cytosolic Prostaglandin E(2) Synthase Results in Decreased Nociceptive Behavior in Rats

Nociception-evoked prostaglandin E(2) (PGE(2)) release in the spinal cord contributes considerably to the development of hyperalgesia and allodynia. Biosynthesis of PGE(2) involves the conversion of arachidonic acid to PGH(2) by cyclooxygenases (COXs), followed by an isomerization of PGH(2) to PGE(2...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Hofacker, Annette, Coste, Ovidiu, Nguyen, Hong-Van, Marian, Claudiu, Scholich, Klaus, Geisslinger, Gerd
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725604/
https://ncbi.nlm.nih.gov/pubmed/16192391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2190-05.2005
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