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The Ubiquitin Ligase MYCBP2 Regulates Transient Receptor Potential Vanilloid Receptor 1 (TRPV1) Internalization through Inhibition of p38 MAPK Signaling

The E3 ubiquitin ligase MYCBP2 negatively regulates neuronal growth, synaptogenesis, and synaptic strength. More recently it was shown that MYCBP2 is also involved in receptor and ion channel internalization. We found that mice with a MYCBP2-deficiency in peripheral sensory neurons show prolonged th...

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Detalhes bibliográficos
Main Authors: Holland, Sabrina, Coste, Ovidiu, Zhang, Dong Dong, Pierre, Sandra C., Geisslinger, Gerd, Scholich, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030370/
https://ncbi.nlm.nih.gov/pubmed/21098484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.154765
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