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Anti-inflammatory Role of Microsomal Prostaglandin E Synthase-1 in a Model of Neuroinflammation

A major immunological response during neuroinflammation is the activation of microglia, which subsequently release proinflammatory mediators such as prostaglandin E(2) (PGE(2)). Besides its proinflammatory properties, cyclooxygenase-2 (COX-2)-derived PGE(2) has been shown to exhibit anti-inflammator...

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Bibliografiske detaljer
Main Authors: Brenneis, Christian, Coste, Ovidiu, Altenrath, Kai, Angioni, Carlo, Schmidt, Helmut, Schuh, Claus-Dieter, Zhang, Dong Dong, Henke, Marina, Weigert, Andreas, Brüne, Bernhard, Rubin, Barry, Nusing, Rolf, Scholich, Klaus, Geisslinger, Gerd
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023527/
https://ncbi.nlm.nih.gov/pubmed/21075851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157362
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