Hedgehog Antagonist REN(KCTD11) Regulates Proliferation and Apoptosis of Developing Granule Cell Progenitors

During the early development of the cerebellum, a burst of granule cell progenitor (GCP) proliferation occurs in the outer external granule layer (EGL), which is sustained mainly by Purkinje cell-derived Sonic Hedgehog (Shh). Shh response is interrupted once GCPs move into the inner EGL, where granu...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Argenti, Beatrice, Gallo, Rita, Di Marcotullio, Lucia, Ferretti, Elisabetta, Napolitano, Maddalena, Canterini, Sonia, De Smaele, Enrico, Greco, Azzura, Fiorenza, Maria Teresa, Maroder, Marella, Screpanti, Isabella, Alesse, Edoardo, Gulino, Alberto
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2005
Sujets:
Development/Plasticity/Repair
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725529/
https://ncbi.nlm.nih.gov/pubmed/16148242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2438-05.2005
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