The tumor suppressor gene KCTD11(REN )is regulated by Sp1 and methylation and its expression is reduced in tumors

A hallmark of several human cancers is loss of heterozygosity (LOH) of chromosome 17p13. The same chromosomal region is also frequently hypermethylated in cancer. Although loss of 17p13 has been often associated with p53 genetic alteration or Hypermethylated in Cancer 1 (HIC1) gene hypermethylation,...

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Библиографические подробности
Главные авторы: Mancarelli, M Michela, Zazzeroni, Francesca, Ciccocioppo, Lucia, Capece, Daria, Po, Agnese, Murgo, Simona, Di Camillo, Raffaello, Rinaldi, Christian, Ferretti, Elisabetta, Gulino, Alberto, Alesse, Edoardo
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Short Communication
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913982/
https://ncbi.nlm.nih.gov/pubmed/20591193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-172
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