The tumor suppressor gene KCTD11(REN )is regulated by Sp1 and methylation and its expression is reduced in tumors

A hallmark of several human cancers is loss of heterozygosity (LOH) of chromosome 17p13. The same chromosomal region is also frequently hypermethylated in cancer. Although loss of 17p13 has been often associated with p53 genetic alteration or Hypermethylated in Cancer 1 (HIC1) gene hypermethylation,...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Mancarelli, M Michela, Zazzeroni, Francesca, Ciccocioppo, Lucia, Capece, Daria, Po, Agnese, Murgo, Simona, Di Camillo, Raffaello, Rinaldi, Christian, Ferretti, Elisabetta, Gulino, Alberto, Alesse, Edoardo
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Short Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913982/
https://ncbi.nlm.nih.gov/pubmed/20591193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-172
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