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Crude Heparin Preparations Unveil the Presence of Structurally Diverse Oversulfated Contaminants
Nowadays, pharmaceutical heparin is purified from porcine and bovine intestinal mucosa. In the past decade there has been an ongoing concern about the safety of heparin, since in 2008, adverse effects associated with the presence of an oversulfated chondroitin sulfate (OSCS) were observed in prepara...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6721129/ https://ncbi.nlm.nih.gov/pubmed/31426507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24162988 |
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