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BRADYKININ FORMING CAPACITY OF OVERSULFATED CHONDROITIN SULFATE CONTAMINATED HEPARIN IN VITRO

Oversulfated chondroitin sulfate (OSCS) contaminated heparin has been associated with severe anaphylactoid reaction (AR), mainly in dialysed patients. Although attributed to bradykinin (BK) released during contact system activation by OSCS, no definitive evidence exists until now for a BK release du...

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Autori principali: Adam, Albert, Montpas, Nicolas, Keire, David, Désormeaux, Anik, Brown, Nancy J., Marceau, François, Westenberger, Benjamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896062/
https://ncbi.nlm.nih.gov/pubmed/20427081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.03.074
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