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Quantitative capillary electrophoresis determination of oversulfated chondroitin sulfate as a contaminant in heparin preparations

A simple, accurate and robust quantitative CE method for the determination of oversulfated chondroitin sulfate (OSCS) as a contaminant in heparin (Hep) preparations is described. After degradation of the polysaccharides by acidic hydrolysis, the hexosamines produced, i.e., GlcN from Hep and GalN fro...

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Detalhes bibliográficos
Main Authors: Volpi, Nicola, Maccari, Francesca, Linhardt, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030564/
https://ncbi.nlm.nih.gov/pubmed/19232311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.02.012
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