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In vitro affinity maturation of antibody against membrane-bound GPCR molecules
G protein-coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, are among the most important targets against which many small molecule drugs have been developed. However, only two antibody drugs targeting GPCRs have been approved for clinical use although many antibody drugs...
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| Publicado no: | Appl Microbiol Biotechnol |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719327/ https://ncbi.nlm.nih.gov/pubmed/31359103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-019-10030-x |
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