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In vitro affinity maturation of antibody against membrane-bound GPCR molecules

G protein-coupled receptors (GPCRs), also known as seven-transmembrane domain receptors, are among the most important targets against which many small molecule drugs have been developed. However, only two antibody drugs targeting GPCRs have been approved for clinical use although many antibody drugs...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Appl Microbiol Biotechnol
Prif Awduron: Wang, Jie, An, Lili, Zhao, Yun, Zhang, Cheng, Li, Shengnan, Ye, Chen, Jing, Shuqian, Hang, Haiying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719327/
https://ncbi.nlm.nih.gov/pubmed/31359103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-019-10030-x
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