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Sorafenib-Induced Apoptosis in Hepatocellular Carcinoma Is Reversed by SIRT1
Sorafenib is a multi-kinase inhibitor and one of the few systemic treatment options for patients with advanced hepatocellular carcinomas (HCCs). Resistance to sorafenib develops frequently and could be mediated by the nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin (SIRT)1. We...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6719220/ https://ncbi.nlm.nih.gov/pubmed/31430957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20164048 |
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