Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression

The protein α-synuclein (αsyn) forms pathologic aggregates in a number of neurodegenerative diseases including Lewy body dementia (LBD) and Parkinson’s disease (PD). It is unclear why diseases such as LBD may develop widespread αsyn pathology, while in Alzheimer’s disease with amygdala restricted Le...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Sorrentino, Zachary A., Goodwin, Marshall S., Riffe, Cara J., Dhillon, Jess-Karan S., Xia, Yuxing, Gorion, Kimberly-Marie, Vijayaraghavan, Niran, McFarland, Karen N., Golbe, Lawrence I., Yachnis, Anthony T., Giasson, Benoit I.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718048/
https://ncbi.nlm.nih.gov/pubmed/31477175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0787-2
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