Neurodegeneration in the age of molecular biology : Abnormal protein folding holds the key to specific treatment

Por Golbe, Lawrence I
Publicado em 2002

Diversity of pathological features other than Lewy bodies in familial Parkinson’s disease due to SNCA mutations

Por Fujishiro, Hiroshige, Imamura, Akiko Yamashita, Lin, Wen-Lang, Uchikado, Hirotake, Mark, Margery H, Golbe, Lawrence I, Markopoulou, Katerina, Wszolek, Zbigniew K, Dickson, Dennis W
Publicado em 2013

A geographical cluster of progressive supranuclear palsy in northern France

Por Caparros-Lefebvre, Dominique, Golbe, Lawrence I., Deramecourt, Vincent, Maurage, Claude-Alain, Huin, Vincent, Buée-Scherrer, Valerie, Obriot, Helene, Sablonnière, Bernard, Caparros, Francois, Buée, Luc, Lees, Andrew J.
Publicado no Neurology (2015)

Study of LRRK2 variation in tauopathy: progressive supranuclear palsy and corticobasal degeneration

Por Sanchez-Contreras, Monica, Heckman, Michael G., Tacik, Pawel, Diehl, Nancy, Brown, Patricia H., Soto-Ortolaza, Alexandra I., Christopher, Elizabeth A., Walton, Ronald L., Ross, Owen A., Golbe, Lawrence I., Graff-Radford, Neill, Wszolek, Zbigniew K., Dickson, Dennis W., Rademakers, Rosa
Publicado no Mov Disord (2016)

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

Por Soldner, Frank, Laganiere, Josee, Cheng, Albert W, Hockemeyer, Dirk, Gao, Qing, Alagappan, Raaji, Khurana, Vikram, Golbe, Lawrence I., Myers, Richard H., Lindquist, Susan, Zhang, Lei, Guschin, Dmitry, Fong, Lauren K, Vu, Joe, Meng, Xiangdong, Urnov, Fyodor D., Rebar, Edward J., Gregory, Philip D., Zhang, H. Steve, Jaenisch, Rudolf
Publicado em 2011

Identification of a Novel Risk Locus for Progressive Supranuclear Palsy by a Pooled Genomewide Scan of 500,288 Single-Nucleotide Polymorphisms

Por Melquist, Stacey, Craig, David W., Huentelman, Matthew J., Crook, Richard, Pearson, John V., Baker, Matt, Zismann, Victoria L., Gass, Jennifer, Adamson, Jennifer, Szelinger, Szabolcs, Corneveaux, Jason, Cannon, Ashley, Coon, Keith D., Lincoln, Sarah, Adler, Charles, Tuite, Paul, Calne, Donald B., Bigio, Eileen H., Uitti, Ryan J., Wszolek, Zbigniew K., Golbe, Lawrence I., Caselli, Richard J., Graff-Radford, Neill, Litvan, Irene, Farrer, Matthew J., Dickson, Dennis W., Hutton, Mike, Stephan, Dietrich A.
Publicado em 2007

Davunetide for Progressive Supranuclear Palsy: a multicenter, randomized, double-blind, placebo controlled trial

Por Boxer, Adam L., Lang, Anthony E., Grossman, Murray, Knopman, David S., Miller, Bruce L., Schneider, Lon S., Doody, Rachelle S., Lees, Andrew, Golbe, Lawrence I., Williams, David R., Corvol, Jean-Cristophe, Ludolph, Albert, Burn, David, Lorenzl, Stefan, Litvan, Irene, Roberson, Erik D., Höglinger, Günter U., Koestler, Mary, Jack, Clifford R., Van Deerlin, Viviana, Randolph, Christopher, Lobach, Iryna V., Heuer, Hilary W., Gozes, Illana, Parker, Lesley, Whitaker, Steve, Hirman, Joe, Stewart, Alistair J., Gold, Michael, Morimoto, Bruce H.
Publicado em 2014

PARK3 Influences Age at Onset in Parkinson Disease: A Genome Scan in the GenePD Study

Por DeStefano, Anita L., Lew, Mark F., Golbe, Lawrence I., Mark, Margery H., Lazzarini, Alice M., Guttman, Mark, Montgomery, Erwin, Waters, Cheryl H., Singer, Carlos, Watts, Ray L., Currie, Lillian J., Wooten, G. Frederick, Maher, Nancy E., Wilk, Jemma B., Sullivan, Kristin M., Slater, Karen M., Saint-Hilaire, Marie H., Feldman, Robert G., Suchowersky, Oksana, Lafontaine, Anne-Louise, Labelle, Nancy, Growdon, John H., Vieregge, Peter, Pramstaller, Peter P., Klein, Christine, Hubble, Jean P., Reider, Carson R., Stacy, Mark, MacDonald, Marcy E., Gusella, James F., Myers, Richard H.
Publicado em 2002

Identification of common variants influencing risk of the tauopathy Progressive Supranuclear Palsy

Por Höglinger, Günter U., Melhem, Nadine M., Dickson, Dennis W., Sleiman, Patrick M.A., Wang, Li-San, Klei, Lambertus, Rademakers, Rosa, de Silva, Rohan, Litvan, Irene, Riley, David E., van Swieten, John C., Heutink, Peter, Wszolek, Zbigniew K., Uitti, Ryan J., Vandrovcova, Jana, Hurtig, Howard I., Gross, Rachel G., Maetzler, Walter, Goldwurm, Stefano, Tolosa, Eduardo, Borroni, Barbara, Pastor, Pau, Cantwell, Laura B., Han, Mi Ryung, Dillman, Allissa, van der Brug, Marcel P., Gibbs, J Raphael, Cookson, Mark R., Hernandez, Dena G., Singleton, Andrew B., Farrer, Matthew J., Yu, Chang-En, Golbe, Lawrence I., Revesz, Tamas, Hardy, John, Lees, Andrew J., Devlin, Bernie, Hakonarson, Hakon, Müller, Ulrich, Schellenberg, Gerard D.
Publicado em 2011

Huntington CAG repeat size does not modify onset age in familial Parkinson’s disease: The GenePD Study

Por McNicoll, Christopher F., Latourelle, Jeanne C., MacDonald, Marcy E., Lew, Mark F., Suchowersky, Oksana, Klein, Christine, Golbe, Lawrence I., Mark, Margery H., Growdon, John H., Wooten, G. Frederick, Watts, Ray L., Guttman, Mark, Racette, Brad A., Perlmutter, Joel S., Ahmed, Anwar, Shill, Holly A., Singer, Carlos, Saint-Hilaire, Marie H., Massood, Tiffany, Huskey, Karen W., DeStefano, Anita L., Gillis, Tammy, Mysore, Jayalakshmi, Goldwurm, Stefano, Pezzoli, Gianni, Baker, Kenneth B., Itin, Ilia, Litvan, Irene, Nicholson, Garth, Corbett, Alastair, Nance, Martha, Drasby, Edward, Isaacson, Stuart, Burn, David J., Chinnery, Patrick F., Pramstaller, Peter P., Al-hinti, Jomana, Moller, Anette T., Ostergaard, Karen, Sherman, Scott J., Roxburgh, Richard, Snow, Barry, Slevin, John T., Cambi, Franca, Gusella, James F., Myers, Richard H.
Publicado em 2008

Replication of association between ELAVL4 and Parkinson disease: the GenePD study

Por DeStefano, Anita L., Latourelle, Jeanne, Lew, Mark F., Suchowersky, Oksana, Klein, Christine, Golbe, Lawrence I., Mark, Margery H., Growdon, John H., Wooten, G. Fredrick, Watts, Ray, Guttman, Mark, Racette, Brad A., Perlmutter, Joel S., Marlor, Lynn, Shill, Holly A., Singer, Carlos, Goldwurm, Stefano, Pezzoli, Gianni, Saint-Hilaire, Marie H., Hendricks, Audrey E., Gower, Adam, Williamson, Sally, Nagle, Michael W., Wilk, Jemma B., Massood, Tiffany, Huskey, Karen W., Baker, Kenneth B., Itin, Ilia, Litvan, Irene, Nicholson, Garth, Corbett, Alastair, Nance, Martha, Drasby, Edward, Isaacson, Stuart, Burn, David J., Chinnery, Patrick F., Pramstaller, Peter P., Al-hinti, Jomana, Moller, Anette T., Ostergaard, Karen, Sherman, Scott J., Roxburgh, Richard, Snow, Barry, Slevin, John T., Cambi, Franca, Gusella, James F., Myers, Richard H.
Publicado em 2008

The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study

Por Latourelle, Jeanne C, Sun, Mei, Lew, Mark F, Suchowersky, Oksana, Klein, Christine, Golbe, Lawrence I, Mark, Margery H, Growdon, John H, Wooten, G Frederick, Watts, Ray L, Guttman, Mark, Racette, Brad A, Perlmutter, Joel S, Ahmed, Anwar, Shill, Holly A, Singer, Carlos, Goldwurm, Stefano, Pezzoli, Gianni, Zini, Michela, Saint-Hilaire, Marie H, Hendricks, Audrey E, Williamson, Sally, Nagle, Michael W, Wilk, Jemma B, Massood, Tiffany, Huskey, Karen W, Laramie, Jason M, DeStefano, Anita L, Baker, Kenneth B, Itin, Ilia, Litvan, Irene, Nicholson, Garth, Corbett, Alastair, Nance, Martha, Drasby, Edward, Isaacson, Stuart, Burn, David J, Chinnery, Patrick F, Pramstaller, Peter P, Al-hinti, Jomana, Moller, Anette T, Ostergaard, Karen, Sherman, Scott J, Roxburgh, Richard, Snow, Barry, Slevin, John T, Cambi, Franca, Gusella, James F, Myers, Richard H
Publicado em 2008

Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy

Por Kouri, Naomi, Ross, Owen A., Dombroski, Beth, Younkin, Curtis S., Serie, Daniel J., Soto-Ortolaza, Alexandra, Baker, Matthew, Finch, Ni Cole A., Yoon, Hyejin, Kim, Jungsu, Fujioka, Shinsuke, McLean, Catriona A., Ghetti, Bernardino, Spina, Salvatore, Cantwell, Laura B., Farlow, Martin R., Grafman, Jordan, Huey, Edward D., Ryung Han, Mi, Beecher, Sherry, Geller, Evan T., Kretzschmar, Hans A., Roeber, Sigrun, Gearing, Marla, Juncos, Jorge L., Vonsattel, Jean Paul G., Van Deerlin, Vivianna M., Grossman, Murray, Hurtig, Howard I., Gross, Rachel G., Arnold, Steven E., Trojanowski, John Q., Lee, Virginia M., Wenning, Gregor K., White, Charles L., Höglinger, Günter U., Müller, Ulrich, Devlin, Bernie, Golbe, Lawrence I., Crook, Julia, Parisi, Joseph E., Boeve, Bradley F., Josephs, Keith A., Wszolek, Zbigniew K., Uitti, Ryan J., Graff-Radford, Neill R., Litvan, Irene, Younkin, Steven G., Wang, Li-San, Ertekin-Taner, Nilüfer, Rademakers, Rosa, Hakonarsen, Hakon, Schellenberg, Gerard D., Dickson, Dennis W.
Publicado no Nat Commun (2015)